Vol. I · No. 286Everything you need. Nothing you don't.Morning Edition

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The Owl · Morning Edition

Two health stories this morning, both about safety signals that are growing louder and the question of who should act.

2Stories
2Min read

Concerns grow over safety of Neurocrine's Prader-Willi drug Vykat XR

Patient advocates and some experts are voicing growing alarm about Vykat XR, Neurocrine Biosciences' therapy for Prader-Willi syndrome, a condition that can cause an insatiable hunger. Since approval 18 months ago, the drug has been linked to seven deaths and nearly 100 hospitalizations. STAT obtained the case reports submitted to regulators through a Freedom of Information Act request. These reports do not prove the drug caused the harm, and many cases involved complex medical problems and multiple medications. Still, some experts say the evidence is enough to conclude Vykat is causing unacceptable harm. This follows an open letter on the safety concerns released two months ago.

Why it mattersYou should know that this is a warning signal, not a proven cause, and it matters most if you or someone you know is affected by Prader-Willi syndrome.

Full story at STAT →

Child e-bike and scooter injuries rise, prompting calls for federal rules

Emergency departments are reporting sharply rising numbers of pediatric trauma cases linked to micromobility devices, a category that includes e-bikes. Our source, a short summary, doesn't give exact counts or say which devices account for most injuries. What it does say is that experts and advocates agree the federal government needs to step in. That makes this a live debate over regulation, not just a trend in hospital data. Details on any specific proposal aren't included, so it's too early to say what rules might look like.

Why it mattersYou may want to watch this if children in your life ride e-bikes or similar devices, since the push for federal standards is gaining support.

Full story at NPR Topics: Health →

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